If you haven't heard of Randy Pausch, then maybe you need to find out who he is. He was a professor at Carnegie Mellon who gave an very inspiring last lecture after discovering he had pancreatic cancer. I've seen the video of the lecture, and it's a very inspiring one. He took the opportunity to tell about his achievements in live, and he gave advice to a packed out auditorium of students on how to achieve their own dreams.
Now there's a book out,The Last Lecture by Randy Pausch, and I really want to give it a read. I'll have to search to see if my local library has it before I buy it, but I might just end up buying it anyway.